Richard Smallwood Research Paper Example | Topics and Well Written Essays - 500 words

Richard Smallwood - Research Paper Example Smallwood started his career as a musician in 1982. Young artist gained popularity very quickly. Already at the beginning of 1980’s Smallwood became one of the most famous and successful gospel musicians. His first project was called The Richard Smallwood Singers. This first album had a success and the next, called Psalms, was even nominated for a Grammy. â€Å"I wanted to write a complete project with songs that dealt with the promises found in His Word so that I could encourage and remind us that God is still in control. Soon after, I began dreaming songs. I have dreamed a few songs before, but I can count the times on one hand that I remembered what I had dreamed after I had awaken. But this time, not only could I remember what I had dreamed but sometimes more than one song would come at the same time and I could barely keep up with them. I knew that God was saying something that we all needed to hear† (Smallwood). The next album was called Textures. It also had a great success and nominated and won. Many famous musicians were interested in his music and recorded it, Yolanda Adams, Karen Clark-Sheard, Destiny's Child are among them. Swallowed accompanied many great singers such as Leontyne Price. The current group of Richard Smallwood is called Vision, he created many great projects with it. After finishing his Master’s degree in 2004, the musician was invited to the Gospel Music Hall of Fame. Richard Smallwood’s life concert was recorded at the Manhattan Center in New York† (Ladywoo Ministry of Music").

Does urea formation have a feedback inhibition mechanism Explain the Essay

Does urea formation have a feedback inhibition mechanism Explain the why or why not - Essay Example Carbomyl phosphate synthase I acts as the rate limiting enzyme in urea cycle. N-acetylglutamate allosterically activates it thus lowering its Km for protein synthesis. Carbomyl Phosphate Synthase I binds with the primary ATP molecule and converts into a vigorous conformation. It then changes into a second form by binding with N-acetylglutamate thus enhancing its own ATP affinity. As a result, a phosphate group is transferred from a subsequent ATP to the enzyme bound carbamate. This changes the carbamate to carbomyl phosphate. This happens according to the Rubio-Britton-Grisolia model. Hence, it is seen that hepatic N-acetylglutamate controls the rate of protein synthesis in the urea cycle, by regulating its rate-limiting enzyme allosterically (Das 475). Arginine does not cause feedback inhibition of Carbomyl PS-1 or OTC but stimulates the activity of acetylglutamate synthetase. However, according to Snodgrass (67), â€Å"in bacteria and fungi, arginine inhibits conversion of glutamate to acetylglutamate†. Also, only at high concentration levels, orthinine transcarbomylase and argininosuccinate synthase undergo feedback inhibition mechanism by citrulline and argininosuccinate, which are their respective